DESCRIPTION
This recombinant Human Fc gamma RIIIB protein is made from HEK293 cells and fused with a polyhistidine tag at the C-terminus.
Known as: CD16b, FCGR3B
BIOACTIVITY
Binds to human IgG as a low affinity receptor.
BACKGROUND
Human Fc gamma RIIIB, also known as CD16b, is a receptor of the Fc region of immunoglobulin γ. This receptor
acts late in the immune response by binding with low affinity and recognizing IgG as aggregates surrounding
multivalent antigens. Human Fc gamma RIIIB is found on neutrophils as well as stimulated eosinophils and acts to
trap immune complexes in the peripheral circulation.
FORMULATION
0.2 μm filtered solution of 30 mM Hepes, 150 mM NaCl, pH 7.5
STORAGE
This protein should be stored at -80°C.
Stable at < -20°C for 3 months or at 4° - 7°C for 3 weeks.
Minimize repeated freeze-thaw cycles.
QUALITY CONTROL
Purity is greater than 95%.
