DESCRIPTION
This recombinant human L-selectin
protein is made from HEK-293 cells. It comprises of the sequence of Human
L-selectin fused with a mouse IgG1 Fc tag at the C-terminus. The predicted MW
is 55 kDa, and observed MW on SDS-PAGE is approximately 75 kDa.
BACKGROUND
Selectins, also designated as CD62
antigens, comprise a family of carbohydrate-binding protein with three members;
E-Selectin, L-Selectin, and P-Selectin. Human L-Selectin (CD62L) is expressed
on lymphocytes and is involved in the entry of these cells into secondary
lymphoid organs.
FORMULATION
0.2 µm filtered solution in 100 mM
HEPES, pH 6.0.
STORAGE
This protein should be stored
at -80°C.
Reconstituted protein solution can
be stored at 2°- 8°C for 2-7 days.
Aliquots of reconstituted protein
solution is stable at < -20°C for 3 months.
QUALITY CONTROL
>95% pure
DOCUMENTS